5 Stocks on the Move on Friday

Aug. 01, 2011 8:30 AM ETSIFY, ACFN, AHCI, GSAT, BHC2 Comments
Alex Shadunsky profile picture
Alex Shadunsky
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These five stocks all moved at least 10% on Friday following company announcements.

Globalstar (GSAT) fell 11% after the retirement of its CEO. The company announced that after the successful implementation of the strategic initiatives he introduced during his tenure, the company has accepted Chief Executive Officer Peter Dalton's request to retire. Executive Chairman and former Globalstar CEO Jay Monroe will immediately resume his operational role as CEO on an interim basis and Mr. Dalton will remain as a special advisor to the interim CEO to assist with transition issues through September 1, 2011. Mr. Dalton is also retiring as a member of Globalstar's Board of Directors. Globalstar has initiated a search for a permanent replacement for Mr. Dalton.

ISTA Pharmaceuticals (ISTA) tumbled 31% after its Phase 3 trial did not meet its primary endpoint. ISTA announced top-line results from the first of its two Phase 3 studies to evaluate the short-term safety and efficacy of two concentrations of REMURA (bromfenac ophthalmic solution for dry eye) in alleviating the signs and symptoms of dry eye disease. The company's Phase 3 safety and efficacy program, which consists of two studies known as EAST and WEST, is being conducted under a Special Protocol Assessment (SPA) agreed upon with the FDA. The top-line results are from the WEST study; the EAST study is now fully enrolled and the company expects to announce top-line results from the EAST study during fourth quarter of 2011.

According to preliminary analysis of the top-line results from the WEST study, while REMURA was highly effective in treating a sign and symptom of dry eye, it was not statistically significantly better than placebo, a common outcome reported in studies testing other dry eye therapies. From baseline, both concentrations of REMURA and the placebo showed highly statistically significant improvement (p < 0.0001) in one sign and one symptom. The co-primary

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