Ionis: One For The Ages

Out of Ignorance
7.38K Followers

Summary

  • Ionis founders designed the company to provide disruptive techniques for drug discovery and commercialization.
  • Ionis has had significant failures in its past which have set the stage for its recent successes, validating its processes and technologies.
  • Going forward, investors can expect excellent buying opportunities in this premium name.
  • As illustrated by its recent Q2 2019 earnings report, Ionis has a superb pathway to long-term success and financial outperformance.
  • In common with every biotech, Ionis has significant challenges; however, Ionis stands tall in its prospects for powering through them with thesis intact.

Over the last several years, I have researched hundreds of emerging biotech companies in various stages of development. I have written articles on many of them which I found the most interesting. I have personally invested in several of these.

Of all these emerging biotech stocks, Ionis (NASDAQ:IONS) stands alone for its combination of current financial viability with exceptional long-term growth potential. As discussed below, Ionis has headwinds over the near to midterm; however, they do not undermine the heady thesis of a biotech grower that is an excellent candidate for accumulation on weakness.

Ionis founders designed the company to provide disruptive techniques for drug discovery and commercialization

Ionis founder and current CEO, Stanley Crooke, often holds forth on the vision underlying Ionis' (formerly Isis) formation. He was in top form for Ionis' shareholders' meeting on 6/6/19. At the time, he reflected on Ionis' 30-year journey as follows:

"Ionis was formed to meet a very, very specific purpose... to create an advance, a new platform for drug discovery that would be significantly more efficient.

We focused on creating a set of molecules that had never been made before and never been considered as possibly drug molecules or medicine molecule, and these molecules reduced the genetic code directly to bind to a set of targets inside the cell that had never been considered as targets for medicines until we did it, and we call that technology antisense. And though we knew nothing about the technology in 1989, I was confident that if we could be successful in creating this technology, it would be significantly more efficient than traditional technologies for drug discovery."

The founding vision for Ionis was to disrupt prevailing techniques for drug discovery which were having a retarding effect on industry productivity. In addition to disrupting drug discovery techniques, Ionis

This article was written by

7.38K Followers
Writing under the pseudonym "out of ignorance", I very much regard investing as a learning process. Investing failures are tuition paid. Investing successes enter the trove of lessons learned. In my Seeking Alpha articles I share my experience from decades of investing and from ~5 years of focused research on a variety of stocks, in recent years with a primary emphasis on healthcare stocks. I greatly appreciate those who take the time to share their reactions to articles, particularly those who share relevant anecdotes and experiences.

Analyst’s Disclosure:I am/we are long IONS NVS. I wrote this article myself, and it expresses my own opinions. I am not receiving compensation for it (other than from Seeking Alpha). I have no business relationship with any company whose stock is mentioned in this article.

I may buy or sell shares in IONS, NVS or AKCA over the next 72 hours.

Seeking Alpha's Disclosure: Past performance is no guarantee of future results. No recommendation or advice is being given as to whether any investment is suitable for a particular investor. Any views or opinions expressed above may not reflect those of Seeking Alpha as a whole. Seeking Alpha is not a licensed securities dealer, broker or US investment adviser or investment bank. Our analysts are third party authors that include both professional investors and individual investors who may not be licensed or certified by any institute or regulatory body.

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