Coronavirus Pandemic Requires Patient Investing And A Focused Portfolio

Mar. 20, 2020 5:30 PM ET, , , , , 21 Comments
Leonard Yaffe
2.73K Followers

Summary

  • The coronavirus pandemic has delivered a shock to our economy, and the severity will be dependent on whether the "curve is flattened".
  • This is a healthcare problem, not an economic one.   Therefore, in my opinion, parallels to 2008, 1999 or 1987 are irrelevant as it relates to the stock market.
  • Mandatory testing, in order to identify asymptomatic, virus positive people would be very beneficial in accelerating the return to normalcy.
  • I have constructed a "coronavirus portfolio" as part of my overall investment philosophy in order to provide some shielding from upcoming challenges.

I view there as being three possible outcomes for the current coronavirus pandemic for the US. The first is that the pandemic overwhelms our healthcare system and shuts down our economy for at least the next six months. I hope this worst case scenario does not occur, but it cannot be dismissed. In my opinion, the early decision of President Trump to limit travel from China was vital in preventing the worse case scenario from unfolding. The second is that social distancing and isolation are effective in "flattening the curve", thereby limiting excessive demands on our healthcare system to a few areas, and the economy begins to recover this summer. The third is that the investigational drugs prove effective in combatting the virus. This would give investors confidence in a business resumption, resulting in a stock market rally. Regardless of which of these sequences unfolds, there will be more harm to the economy.

I have chosen to invest a portion of my portfolio in stocks that should perform well as the pandemic worsens. Regarding pharmacotherapy, I have purchased Gilead (GILD), which is testing remdesivir, Regeneron (REGN), which is testing Kevzara, is also working on an antibody-based therapeutic, and separately is benefitting from side effect issues associated with a Novartis (NVS) drug competing with Eylea, and Hepion (OTC:HEPA), a microcap stock I have previously recommended for its drug CRV431, which is in Phase 1 clinical study for non-alcoholic steatohepatitis ("Nash"). It appears that this drug, a cyclophillin inhibitor, may have efficacy in pulmonary fibrosis and in blocking coronavirus replication. In fact, in a 2018 article in Virology, the authors stated that cyclophillin inhibitors can block coronavirus replication in cell culture. In 2020 article in Antiviral Research, authors commented that cyclosporine A

This article was written by

2.73K Followers
I am an MD by background who runs a healthcare hedge fund. I worked as a sell-side medical analyst for 20 years, covering pharmaceuticals, medical devices, PBMs and drug distributors.

Analyst’s Disclosure:I am/we are long GILD, REGN, AHPI, GNMK, HEPA. I wrote this article myself, and it expresses my own opinions. I am not receiving compensation for it (other than from Seeking Alpha). I have no business relationship with any company whose stock is mentioned in this article.

Seeking Alpha's Disclosure: Past performance is no guarantee of future results. No recommendation or advice is being given as to whether any investment is suitable for a particular investor. Any views or opinions expressed above may not reflect those of Seeking Alpha as a whole. Seeking Alpha is not a licensed securities dealer, broker or US investment adviser or investment bank. Our analysts are third party authors that include both professional investors and individual investors who may not be licensed or certified by any institute or regulatory body.

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Related Stocks

SymbolLast Price% Chg
GILD--
Gilead Sciences, Inc.
REGN--
Regeneron Pharmaceuticals, Inc.
NVS--
Novartis AG
HEPA--
Hepion Pharmaceuticals, Inc.
GNMK--
GenMark Diagnostics, Inc.

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