Altimmune: The Late Bloomer Of The COVID-19 Biotech World, The Best Is Yet To Come

Sep. 17, 2020 12:15 AM ETAltimmune, Inc. (ALT) Stock, , , , , 33 Comments
BiotechValley Insights
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Summary

  • I am bullish on Altimmune because of their two COVID-19 programs, T-COVID and AdCOVID. Specifically, T-COVID is reminiscent of a Tamiflu, but for COVID-19.
  • AdCOVID has all the characteristics that WHO is looking for: sterilizing immunity (prevention of infection and transmission), safety, a single-dose administration, intranasal, and room temperature storage.
  • The OWS vaccines will not be effective enough to end this pandemic. As such, COVID-19 will linger for years until approval of an effective vaccine that is able to induce sterilizing immunity.
  • The three primary risks to ALT's shareholders are: the early abatement of the COVID-19 pandemic before ALT's products launch, lack of financing and manufacturing capacity, and lastly - clinical trial failures.

Source: Altimmune Website

Company Background:

Altimmune (NASDAQ:ALT) is a US biopharmaceutical company based in Gaithersburg, Maryland, USA, which focuses on developing treatments for liver disease, immune-modulating therapies, and vaccines. Altimmune has various pre-clinical to clinical pipeline candidates for NASH (ALT-801), chronic hepatitis B (HepTcell), cancer (ALT-702), and intranasal vaccines (NasoVAX and NasoShield). I am particularly interested in ALT's COVID-19 programs because it is the most important short-term driver for ALT's stock price. I believe its NASH and chronic hepatitis B initiative will emerge as encouraging assets in the long term. The promising outlook for AdCOVID and T-COVID in the near term has the potential to draw investors' attention to ALT's other pipeline candidates. Moreover, due to the COVID-19 pandemic, awareness of various vaccines and infectious diseases has improved, and I expect a strong tailwind for differentiated vaccine developers like ALT over the next decade.

ALT's Pipeline and Upcoming Catalyst for ALT:

Drug Name: Indication: Last Event: The phase of development: Upcoming Catalyst Date
AdCOVID COVID-19 08/25/2020 Preclinical 10/01/20 - 12/31/20
T-COVID COVID-19 06/29/2020 IND Now - 09/30/20
ALT-702 Solid Tumors 01/23/2020 Preclinical Now - 12/31/20
ALT-801 Non-Alcoholic Steatohepatitis (NASH) 08/26/2020 Preclinical 10/01/20 - 12/31/20
DepoVax-Anthrax Anthrax Infection (Anti-bacterial) 05/04/2017 Suspended
Flunisyn Seasonal Influenza Vaccines 05/04/2017 Suspended
Hepsyn-B Hepatitis B Prevention (Vaccines, Antiviral) 05/04/2017 Suspended
HepTcell Hepatitis B Prevention (Vaccines, Antiviral) 06/22/2020 I 10/01/20 - 12/31/20
NasoShield Anthrax Infection (Antibacterial) 08/07/2020 I Now - 09/30/20
NasoVAX Seasonal Influenza Vaccines 08/28/2020 II Now - 12/31/20
NasoVAX Pandemic Influenza Vaccines 03/19/2019 II
NasoVAX COVID-19 06/24/2020 Preclinical Now - 09/30/20
Oncosyn Cancer 12/13/2018 Preclinical
rBChE Biodefense 05/04/2017 Suspended
SP-1373 Non-Alcoholic Steatohepatitis (NASH) 07/15/2019 Preclinical Now - 12/31/20
SP-1373 Diabetes Mellitus, Type II 06/11/2017 Preclinical
SparVax Anthrax Infection (Antibacterial)

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