Mereo BioPharma: Good Science, Fairly Valued

(8min)

Summary

  • Mereo Pharma is transitioning to a rare disease focus, with lead candidate setrusumab showing promising phase 2 and 3 data for Osteogenesis Imperfecta.
  • Setrusumab's phase 2 ORBIT study showed a 67% reduction in fracture rate and significant bone density improvements, outperforming current treatments like bisphosphonates.
  • Mereo's financials show a market cap of $467mn and a cash runway of 8-10 quarters, but the small market limits potential returns.
  • Despite promising data, the small market size for OI leads me to believe Mereo is fairly valued, so I recommend staying on the sidelines.

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I covered Mereo BioPharma Group plc (NASDAQ:MREO) in December 2023. At that time, they were transitioning from an anti-TIGIT developer to a rare disease one. I covered their past history in some detail in that article

This article was written by

Avisol Capital Partners is made up of a team of medical experts, finance professionals and techies, all of whom invest their own money in the picks they share. They aim to help readers find the middle ground between value and growth investing, as they demystify the biopharma industry.

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Analyst’s Disclosure: I/we have no stock, option or similar derivative position in any of the companies mentioned, and no plans to initiate any such positions within the next 72 hours. I wrote this article myself, and it expresses my own opinions. I am not receiving compensation for it (other than from Seeking Alpha). I have no business relationship with any company whose stock is mentioned in this article.

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